Embracing Early Detection

I recently sat down with David Medvedeff, our Radence CEO, at Palm Beach’s famed The Breakers Resort to talk about Radence, as we anticipate the opening of the West Palm Beach Innovation Hub and member office this summer. As a serial successful health care startup leader, David knows better than most what is missing for patients, and their doctors, looking for care to extend health span and reduce chronic illness using science-backed testing.

He explained that in many areas of healthcare, progress is measured by access to more — more tests, more data, more interventions. As a trained pharmacist, he has seen first-hand that more doesn’t always mean better, and meaningful impact is the result of personalization. Without thoughtful curation, an abundance of medical information can overwhelm rather than inform. The vision for Radence, first incubated within RA Capital Management, a leader in biopharmaceutical innovation, is to develop a different approach to early detection and preventive care: one grounded in scientific discipline, careful prioritization, and collaborative thinking.

The goal isn’t to flood the system with diagnostics. It’s to choose the right test, for the right person, at the right time — and to do so in partnership with concierge and primary care doctors and medical team who already play a central role in  caring for their patients. Proven advancements in managing the risks of chronic illness through insights at the cellular level have changed the game when it comes to optimizing health span, however, their wider use is only just beginning.

“We’re not trying to replace anyone’s doctor,” Most physicians we work with have decades-long relationships with their patients.” He emphasized, “Our job is to complement their practice, to give Radence members and their doctors access to research and precision data they wouldn’t otherwise have. Radence is concierge science, tirelessly supporting our stakeholders as their partner in precision medicine, no different than how a cardiologist or neurologist would be engaged.”

Recognizing the busy lives and needs of their clients inspired a shift in the way the company is set up to accommodate member care wherever they are in the world. Radence avoids the typical health-tech formula. There are no company-owned scanning centers or fleets of proprietary machines. Instead, it’s a distributed network — coordinated testing in the locations where members reside, relying on best-in-class verified expert partners rather than an in-house infrastructure. The intent is to remain adaptable and to avoid a one-size-fits-all battery of tests and scans to justify fixed costs.

“Once a company buys an MRI or a PET scanner, the business becomes about utilization. In that model, whether an individual needs a given test becomes secondary,” David said. “We’ve intentionally stayed away from that. Radence takes a more deliberate approach, focused on personalized precision care.”

In my time standing up this business with our clinical team, I have learned that our personalized precision approach happens across several layers with the best-informed proprietary protocols in the industry: genomic sequencing, imaging, biomarkers, cognitive assessments, and comprehensive consultations. Each test result is evaluated in a specific sequence not only on what it can reveal, but on what it might obscure or complicate. This multi-modal approach is a sharp contrast to much of what is being promoted today to extend health span.

Behind the scenes, the work is supported by medical experts, scientists, and research partners who monitor emerging technologies, clinical trials, and scientific advancements. This ensures that the care and service Radence members receive is the most leading-edge option science has to offer.

Members begin with a comprehensive baseline evaluation, followed by tailored engagement throughout the year. This may include additional testing, risk modeling, or targeted follow-up depending on each member’s personal health profile. Over time, the goal is to create a deeper and more accurate understanding of how your health changes and what steps might matter most going forward.

Radence believes that in providing the best forecast of members’ future health, the emphasis remains on context over volume.

“There’s a temptation to think that more information is always better,” David said. “But without structure, it becomes noise and can seed anxiety for both the patient and doctor. Our role is to interpret and prioritize, to give members and their doctors relevant, actionable health insight focused on enhancing peace of mind. That’s why our protocols are tailored not only to biological risk but also to psychological readiness.”

That philosophy extends to the thoughtful way information is communicated. When results are shared with physicians, the aim is to avoid overwhelming with raw outputs, and offer clear, clinically relevant reports they can use in decision-making. This serves to support the physician’s role rather than compete with it.

Radence is focused on what the company calls Health Assurance. For many, time and access can be limiting factors. By coordinating services locally, where members reside, delivering health insights early, and partnering with medical teams, Radence builds trust and offers a seamless, elevated, member experience. What emerges is a higher standard of care empowering members to make data-driven decisions early enough to impact future outcomes and change what health care will be for generations to come.

While the healthcare industry is often crowded with buzzwords, Radence is building something deeper, more rigorous, and far more human. At the heart of Radence’s model is early detection for disease interception and enduring support. The Radence journey is about creating a lifelong process of understanding, protecting, and optimizing the health of our members.

Led by Chief Medical Officer Dr. Julie Chen, Radence is defining a higher standard of care than anything else available today. She is a rising star in the field of health span extension through precision medicine in her approach to caring for members.

Precision programs often involve many modalities and a great deal of data. At Radence, the bar is much higher. Our interpretation of precision medicine involves a multimodal approach, innovative tools, and high-quality data to provide actionable insight that can impact our members’ day-to-day quality of life.

“The beauty and artisanship of our approach lies in selecting the right tools to get an accurate picture of each individual from their health data and creating a highly personalized action plan tailored to each member,” said Dr. Julie Chen. “Providing precision data gives our members some control over their health span. It’s a partnership. Radence gives members clear data-driven guidance and recommendations for an optimized pathway to optimal outcomes. What matters most is the quality of what Radence members receive. From the clinical on-science precision of early detection testing to the accuracy of who our members truly are — that is what leads to reproducibility in our interpretations. Our care model is designed for scientific integrity at every level.”

Radence’s multimodal, multi-layered approach to early detection triangulates insights across tools, organ systems, and time, she explained. “It’s about doing the right tests, not over testing. Quality vs. Quantity,” Dr. Chen said. “It’s about building a more complete picture of your health and reducing the chance of false positives or false negatives that could lead to either unnecessary panic or missed opportunity.”

“While there is significant value in having data, there is an intentional approach to why we gather that data and what we do with it,” she said. “It’s aligned with desired outcomes and personal goals. This is not about gathering random data. The how and the what are based on the why, based on each person’s intentions, goals, and risk factors. That makes it personalized.”

At Radence, we walk with you. We use what we learn to create a mutual understanding of your health at a cellular level.

“Health is a moving target,” Dr. Chen said. “Diseases evolve. Physiology changes. We grow with our members, so we can see how their bodies are evolving, whether they’re moving toward disease or away from it.”

This continuous relationship enables Radence to detect small shifts that might otherwise be missed. “Our longitudinal approach isn’t just about diagnostics. It’s about building a true health partnership,” she said. “One that is alert, adaptive, and deeply informed.”

While Radence focuses on science and personalized precision care, what truly guides this innovative model is something deeply human: care as if you’re family.

“When I meet one-on-one with our members, I always ask myself: ‘If this was my parent, my child, my best friend — how would I approach this?’  That’s the lens we bring to every decision,” said Dr. Chen. “Every clinician at Radence is trained not only in the protocols and tools, but in this philosophy. It’s not enough to be highly skilled. Our providers must be deeply invested. If they’re not doing that, they’re not part of Radence.”

Medicine moves fast — and Radence does more than keep pace. We lead.

The Radence model is built to never stand still. Whether it’s adding new genes to a genomic panel after just one insight or reevaluating a testing protocol after a single ambiguous case, our clinical team is in constant conversation about continuous improvement.

“There is no static,” Dr. Chen said. “If I don’t like what I’m seeing in a meeting, we iterate. Immediately.”

This commitment to refinement is part of what makes Radence unique.

“We aren’t simply offering what’s available, we are building what should exist,” she said. “Every encounter, every report, every protocol is held to a higher standard, constantly evaluated and pressure tested, focused on the drive to be the best and deliver the best. Always.”

Consistency is not a luxury. It’s a clinical imperative for Dr. Chen and her team at Radence. From the quality of imaging machines to the communication style of our clinicians, Radence is working to ensure that every touchpoint delivers the same level of excellence.

“Whether you’re speaking to a radiologist, internist, or nurse practitioner, you are engaging with one unified standard of care. That level of consistency is rare. And it’s intentional,” Dr. Chen said.

“Radence is not just a system. It’s a mindset. A culture of care rooted in curiosity, rigor, and love. Our members are not patients, they are part of the Radence family,” Dr. Chen said.

To care for someone as if they are family is a high bar.

“It means we don’t accept good enough. It means we question everything. And it means that we are always watching, learning, evolving — so that we can see the stumble before it happens,” Dr. Chen said. “That’s the Radence Standard of Care.”