Designed by scientists for their families, personalized for yours.
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Meet Radence's Chief Medical Officer
When the evidence supports a new approach, we bring it to you years before it becomes standard practice. When science advances beyond standard guidelines, your care can evolve with it. And when unproven treatments appear, we cut through the hype with clear analysis, honest context, and recommendations that make sense for you.
To develop each member's unique prevention plan, Radence considers all technologies, modalities, specialties, organ systems, and disease areas. Our teams evaluate the latest science and, when it's relevant and appropriate, can help members access current and upcoming clinical trials.
A test earns its place in your protocols only if the data it provides can change what we do. Our goal is to help preserve more healthy years for you and the ones you love, not create anxiety about findings no one can act on.
If a health concern turns up, we provide thorough analysis and clear next steps. We keep your existing doctors in the loop and your Radence concierge can handle any subsequent scheduling and logistics on your behalf.
Radence works alongside your primary care or concierge physician to add what a typical routine visit can’t: advanced diagnostics and a thorough, current view of the science that matters for you. We keep your existing care team informed of every finding. When a treatment is supported by the science but your existing care team isn’t comfortable ordering it, we help coordinate access through the right specialist. And we explain when the evidence supports going beyond routine guidelines, when restraint is the right call, and why a recommendation makes sense for you.
A PERSONAL CONVICTION
Radence began with a question Peter Kolchinsky, PhD, Founder of Radence and Co-Founder of the life sciences investment firm RA Capital Management, put to his colleagues: what care would we want for the people we love?
Investing in new medicines means doing diligence the way few patients ever can. Before backing a therapy, RA Capital's TechAtlas team of MDs and PhDs doesn't just ask one or two doctors what they think - they ask dozens. That taught the team something uncomfortable: experts routinely disagree, and medicine is far more uncertain than anyone facing a consequential decision for themselves or someone they love is ever told. So when their friends and family called in a medical crisis, caught between conflicting advice, they learned the real question wasn't which doctor to trust. It was why. “Why can’t they just agree on what’s best when they’re all looking at the same data? I don’t know how to choose!” Getting to the underlying science let us lay out the real trade-off between risk and benefit, what some doctors were overlooking, and what the recommended course of action solved for. That understanding gave people peace of mind, and the clarity to make an informed choice for themselves.
Radence brings that RA Capital capability to clinical practice, with TechAtlas scientific analysis built in, so every member gets the why behind their options and the confidence that they are doing right by themselves and their families.
“I couldn’t accept the idea that my family might get the wrong medical advice when I had it in my power to examine the science myself and steer them toward better care.That's why we created Radence.”
Founder, Radence | Co-Founder, RA Capital
EARLIER DETECTION. PERSONALIZED PREVENTION.
A test earns its place in your protocol only if its results can change what we do next. Some are simple, some require scanners, and all are chosen to generate actionable data.
The assessments shown represent the range of testing available through Radence. Your physician determines which tests are appropriate based on your medical history, individual risk factors, and clinical needs. Not every assessment is recommended for every member.
Is there something a routine screening might miss?
What we test
WHY
To determine when your screening starts, how often it repeats, and which findings go straight to a specialist. Colorectal screening, for example, starts at 35.
Is plaque building while my cholesterol looks normal?
What we test
WHY
To determine whether to lower your LDL earlier than standard guidelines suggest, how far it should come down, and how closely we should monitor it. Standard panels can't tell us this.
Could my brain be changing in ways I won’t notice for years?
What we test
WHY
To create a baseline to compare against for years, and determine how closely to monitor given your genetic risk.
Is my metabolism drifting before my glucose test shows it?
What we test
WHY
To identify the focus of your nutrition and lifestyle recommendations, and whether follow-up testing is needed.
What does my history suggest I test for?
What we test
WHY
To identify if your prevention protocol would benefit from targeted follow-up rather than relying on the standard menu.
200+ assessments are available across five modalities. Yours include the ones that could change a decision for you. Your assessment protocol is reviewed annually and evolved as necessary.
| Modality | What it covers | Examples |
|---|---|---|
| ModalityBlood and biomarkers | What it coversMore than 150 biomarkers, drawn by our phlebotomist | ExamplesAdvanced lipid markers, glucose and insulin markers, hormones, thyroid, inflammation, nutrients, brain-health markers, cancer and plasma-cell screening, autoimmune panels |
| ModalityAdvanced imaging | What it coversWhole-body BioAtlas MRI, plus heart, vascular and focused imaging as your history indicates | ExamplesEchocardiogram, EKG, carotid ultrasound, coronary CT angiography, DEXA, low-dose lung CT, breast imaging, cardiac MRI |
| ModalityGenetics | What it coversWhole-genome sequencing, performed once and re-interpreted each year | ExamplesA panel of nearly 3,000 genes, medication genetics, polygenic risk scores, genetic counseling |
| ModalityAt-home testing | What it coversCollected in private and shipped to partner laboratories | ExamplesMulti-cancer early detection blood test, colorectal screening, hormone and nutrition panels, gut testing |
| ModalityWearables | What it coversUsed when clinically indicated | ExamplesExtended heart-rhythm monitor, at-home sleep apnea test, continuous glucose monitor |
BioAtlas is Radence's own whole-body MRI protocol, built on higher resolution 3-Tesla scanners with advanced coils and AI denoising, and read by select radiologists trained on it. In comparison with typical whole-body MRI on lower resolution 1.5-Tesla scanners: BioAtlas scan time is 90 minutes versus 15-60 for standard MRI; BioAtlas slices are spaced 4.5 mm and are gapless versus every 5-6 mm with gaps with standard imaging; BioAtlas includes 2-3 imaging planes per region versus 1-2. The end result is superior imaging that makes it easier to compare future scans with prior ones to detect whether any finding might have been there all along or is new and potentially actionable.
The whole genome is read, not selected regions, and interpreted against a panel of nearly 3,000 genes with credible evidence linking variants to disease. Variants are classified against current clinical evidence and explained by certified genetic counselors. Polygenic risk scores are reported only where the clinical evidence is confirmed.
Annual cognitive screening helps establish a baseline to identify meaningful changes over time. When appropriate, Radence can coordinate optional, comprehensive neuropsychological evaluations with independent specialists, at an additional cost to the member. Findings are considered alongside brain MRI, blood markers, and APOE genetics to provide a more complete picture of cognitive health.
Mammography with density assessment, breast MRI for dense tissue or elevated risk (e.g., based on cancer-gene status), a full hormone and thyroid panel, and bone-density screening from age 35 rather than the standard 65.
RADENCE MEMBER EXPERIENCES
“I Got Support For a Complex Diagnosis”
For years, my autoimmune diagnosis was something that I suffered more or less alone. Most doctors wanted to treat the symptoms in front of them, rather than investigating the root cause – despite my strong desire to dig deeper. They pushed medication on me, despite that not being a route I wanted to take. Dr. Chen has been a breath of fresh air, approaching me with genuine curiosity and a wealth of knowledge. Her evaluation of my health picture has been thorough and thoughtful. She has ordered tests I’d never even heard of because she shares my desire to find actual answers – not just manage my condition. Blood draws were convenient, and done on my schedule.
J.D., Radence Member
“I Finally Understand the Reasoning”
You just don’t look at medical guidelines the same after you've read a Radence protocol explaining the rationale for why they screen earlier for colorectal cancer, how they prevent osteoporosis, and what they would do about a finding of asymptomatic Alzheimer’s. Everything is rooted in science and clearly laid out. If only this is what insurance covered for everyone.
P.K., Radence Member
“My Decision Was Informed By The Trade-offs”
Until Radence showed me the science, no doctor could explain the trade-offs of taking more or less aggressive actions such as giving up my breasts and ovaries after learning I had a BRCA mutation that increased my risk of multiple cancers. When I finally saw the risks fully quantified by my Radence clinical team, I made the choice that was right for me - and very different from what my first doctor had recommended.
E.J., Radence member
Radence is a comprehensive concierge science-medicine practice. We work with your existing doctors and the whole medical system to make the right testing and treatments available to you, and to ensure your decisions are guided by the latest science. We stay with you as your health and the evidence change, coordinating specialists and - when appropriate - assisting in identifying promising clinical trials that keep you as healthy as you can be for as long as possible.
The right time to join Radence is now - the better your current health, the more we have to work with to protect and maintain together. We start by assessing and establishing lifelong benchmarks, to identify and mitigate health issues before they become problems. Radence is built to be your ongoing partner, continuously evolving your protocols to deliver the best preventative care possible, to keep you as healthy as possible, as long as possible.
A dedicated concierge and clinical team, a testing plan built around you (blood, imaging, genetics, cognitive assessment and wearables as indicated), clinician review of every result, coordination with your other doctors and specialists, a personal preventative care plan, and an annual plan review and update.
Availability and logistics depend on where you live. Request a membership conversation to discuss current eligibility and the locations available to you.
Radence doesn't replace primary care, treat active disease, bill insurance, issue prescriptions, perform invasive procedures, or provide emergency care. Members with late-stage disease or cancer, advanced dementia, or on dialysis aren't eligible at this time, but we look forward to offering members help in identifying the most promising clinical trials relevant to their situation.
We don’t sell or rent your personal information. We use physical, technical and administrative safeguards to protect it, and you can ask us to access, update or delete it. Health information you share as a patient may be covered by HIPAA, and Radence provides additional privacy notices for specific services. Read our full Privacy Policy. Questions: info@radence.com.
Membership pricing is shared during a membership conversation, along with what is included and any details relevant to your location. Request a membership conversation for current pricing and eligibility information.